سامانه مدیریت نشریات علمی دانشگاه شهید بهشتی

رجبی, علی, اکبرنژاد, علی, سیاه‌کوهیان, معرفت, یاری, مرتضی. (1400). پاسخ مقادیر سرمی TNF-α ،ا 6-IL و نیمرخ لیپیدی به دو توالی تمرین هوازی همحجم در زنان میانسال چاق مبتلا به دیابت نوع دو. , 14(1), 59-72. doi: 10.52547/joeppa.14.1.59
علی رجبی; علی اکبرنژاد; معرفت سیاه‌کوهیان; مرتضی یاری. "پاسخ مقادیر سرمی TNF-α ،ا 6-IL و نیمرخ لیپیدی به دو توالی تمرین هوازی همحجم در زنان میانسال چاق مبتلا به دیابت نوع دو". , 14, 1, 1400, 59-72. doi: 10.52547/joeppa.14.1.59
رجبی, علی, اکبرنژاد, علی, سیاه‌کوهیان, معرفت, یاری, مرتضی. (1400). 'پاسخ مقادیر سرمی TNF-α ،ا 6-IL و نیمرخ لیپیدی به دو توالی تمرین هوازی همحجم در زنان میانسال چاق مبتلا به دیابت نوع دو', , 14(1), pp. 59-72. doi: 10.52547/joeppa.14.1.59
رجبی, علی, اکبرنژاد, علی, سیاه‌کوهیان, معرفت, یاری, مرتضی. پاسخ مقادیر سرمی TNF-α ،ا 6-IL و نیمرخ لیپیدی به دو توالی تمرین هوازی همحجم در زنان میانسال چاق مبتلا به دیابت نوع دو. , 1400; 14(1): 59-72. doi: 10.52547/joeppa.14.1.59

پاسخ مقادیر سرمی TNF-α ،ا 6-IL و نیمرخ لیپیدی به دو توالی تمرین هوازی همحجم در زنان میانسال چاق مبتلا به دیابت نوع دو

نشریه فیزیولوژی ورزش و فعالیت بدنی
دوره 14، شماره 1 - شماره پیاپی 27، فروردین 1400، صفحه 59-72    اصل مقاله (1.39 M)
نوع مقاله: علمی - پژوهشی
شناسه دیجیتال (DOI): 10.52547/joeppa.14.1.59
نویسندگان
علی رجبی1؛ علی اکبرنژاد* 2؛ معرفت سیاه‌کوهیان1؛ مرتضی یاری2
1گروه تربیت بدنی و علوم ورزشی، دانشکدۀ علوم تربیتی و روان‌شناسی، دانشگاه محقق اردبیلی، اردبیل، ایران
2دانشکدۀ تربیت بدنی و علوم ورزشی، دانشگاه تهران، تهران، ایران
چکیده
هـدف: تحقیـق حاضـر بـا هـدف مقایسـۀ اثـر دو توالـی مختلـف تمریـن هـوازی بـا حجـم یکسـان و مانـدگاری پـس از آن بـر سـطوح سـایتوکاینهای التهابـی 6-IL،ب α-TNF و نیمـر خ لیپیـدی در زنـان چـاق مبتـا بـه دیابـت نـوع دو انجـام گرفـت. روشهـا: بدینمنظـور، 36 زن چـاق مبتـا بـه دیابـت نـوع دو بهصـورت تصادفـی بـه سـه گـروه مسـاوی 12 نفـره تقسـیم شـدند. گـروه یـک و دو بـه مـدت 8 هفتـه )گـروه یـک= 3 جلسـه و گـروه دو= 6 جلسـه در هفتـه، بـا حجـم یکسـان( تمریـن هـوازی بـا شـدت 60 تـا 75 درصـد ضربـان قلـب بیشـینه انجـام دادنـد. نمونهگیریهـا در مرحلـۀ پیشآزمـون، 48 سـاعت و دو هفتـه پـس از آخریـن جلسـۀ تمرینـی انجـام گرفـت. در ادامـه متغیرهـای بیوشـیمیایی بـا روش االیـزا اندازهگیـری شـد. بـرای مقایسـۀ نتایـج درونگروهـی از آزمـون تحلیـل واریانـس بـا اندازهگیـری مکـرر همـراه بـا آزمـون تعقیبـی بونفرونـی و بـرای بررسـی نتایـج بینگروهـی از تحلیـل واریانـس یکراهـه بـا آزمـون تعقیبـی توکـی اسـتفاده شـد. نتایــج: پــس از 8 هفتــه مداخلــه، نتایــج درونگروهــی در متغیرهــای 6-IL،ب α-TNF ،بTG و کلســترول تــام تنهــا در گــروه تمرینــی یــک، در پسآزمــون و مانــدگاری در مقایســه بــا پیشآزمــون کاهــش معنــادار نشــان داد )05/0>P .)همچنیــن نتایــج بینگروهــی نشــاندهندۀ اختــاف معنــادار متغیرهــای مذکــور بیــن گروههــای یــک بــا کنتــرل و یــک بــا دو بــود )05/0>P)؛ درحالیکـه بیـن گـروه دو بـا کنتـرل در مراحـل پسآزمـون و مانـدگاری اختـاف زیادی مشـاهده نشـد )05/0
P .)میـزان مانـدگاری کاهـش در متغیـر وزن، چربـی بـدن، شـاخص تـودۀ بدنـی، نسـبت بـه مرحلـۀ پیشآزمـون تنهـا در گـروه یـک، همچنـان معنـادار بـود )05/0>P.) نتیجهگیــری: نقــش تمریــن ورزشــی بــا مــدت زمــان بیشــتر نســبت بــه تکــرر در جلســات تمرینــی کوتاهمــدت میتوانــد موجــب تعدیــل بهتــر 6-IL،ب α-TNF و نیمــر خ لیپیــدی در زنــان چــاق مبتــا بــه دیابــت نــوع دو شــود.
کلیدواژه‌ها
اینترلوکین- 6؛ چاقی؛ دیابت قندی نوع دو؛ عامل نکروز توموری آلفا؛ ورزش زنان
عنوان مقاله [English]
The response of TNF-α, IL-6 serum levels and lipid profiles to two aerobic training frequencies with the same volume in obese middle-aged women with type 2 diabetic
نویسندگان [English]
ali rajabi1؛ ali akbarnejad2؛ Marefat siahkohian1؛ morteza yari2
1Department of Physical Education and Sport Sciences, Faculty of Educational Sciences and Psychology, Mohaghegh Ardabili University, Ardabil, Iran
2Faculty of Physical Education and Sports Sciences, University of Tehran, Tehran, Iran
چکیده [English]
Purpose: The aim of this study was to comparison of the effect of two different frequencies of aerobic exercise with the same volume and detraining period on the levels of IL-6, TNF-α and lipid profiles in obese middle-aged women with type 2 diabetes.
Methods: Thirty-six obese women age?? with type 2 diabetes were randomly divided into three groups of 12 equal members (Group I = three sessions and group two = six sessions per week, with the same volume). Subjects in Groups I and II performed aerobic training for eight weeks with an intensity of 60 to 75% of the maximum heart rate and the same volume. Samples were taken Pre-test, 48 hours and two weeks after the last training session. Biochemical variables were measured by ELISA method. The repeated measure of Analysis of Variance (ANOVA) with Bonferroni’s post hoc test was used to evaluate intra-group changes and One-way ANOVA with post-test Tukey test were used to evaluate the inter-group outcomes at each stage.
Results: After eight weeks of interventions, the intergroup results showed that TNF-α, IL-6, TG and total cholesterol were only significantly reduced in Group I (P <0.05). Also, the between-group results showed a significant difference between groups one with control, and I with two in the above variables (P < 0.05). However, there was no significant difference between the group two with control in the post-test and detraining stages (P <0.05). And there was no significant difference between group two and control in post-test and detraining stages (P <0.05). Moreover, results in weight, body fat and BMI variables were only significantly reduced in Group I (P <0.05).
Conclusion: The effect of exercise training with a longer duration than the frequency in short-term training sessions was better in controlling the IL-6, TNF-α and lipid profiles in obese women with type 2 diabetes.
کلیدواژه‌ها [English]
Diabetes Mellitus Type 2, Exercise, Obesity, Women, TNF-alpha, Interleukin-6, Tumor Necrosis Factor-alpha
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